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KMID : 1114620140110020129
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Journal of the Korean Society for Breast Screening
2014 Volume.11 No. 2 p.129 ~ p.134
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MRI-Guided Vacuum-Assisted Breast Biopsy: Initial Results
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Cho Nariya
Shin Sung-Ui
Chu A-Jung
Moon Woo-Kyung
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Abstract
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Purpose: To analyze technical success rate, positive predictive value (PPV), histologic underestimation, false negative rate of MR-guided vacuum assisted breast biopsy performed in our institution.
Materials and Methods: Between 2010 and 2013, for the 44 women (mean age, 50.5 years; range 32-69), technical success rate, PPV, histologic underestimation rate, and false negative rate were analyzed. PPV was defined as the number of cases proven to be cancers divided by the total number of cases. Atypical ductal hyperplasia (ADH) underestimation rate was defined as the number of cases proven to be cancers at surgical excision divided by the number of cases with ADH at biopsy. Ductal carcinoma in situ (DCIS) underestimation rate was defined as the number of cases proven to be invasive cancers divided by the number of cases with DCIS. False negative rate was defined as the number of cases of malignancy at 1- year follow-up divided by the number of cases with benign histology at biopsy.
Results: The technical success rate was 97.7% (43/44). The reason for the failure was a deep lesion location. The PPV was 22.7% (10/44). ADH underestimation rate was 33.3% and DCIS underestimation rate was 28.6% (2/7). False negative rate was 0%, as no cancer was found in the 34 benign lesions at a mean of 18 month follow-up (range, 12-36 months).
Conclusion: MRI-guided vacuum-assisted biopsy is an accurate method alternative to the surgical excision, considering the acceptable technical success rate, PPV, histologic underestimation rate, and false negative rate in our institution.
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KEYWORD
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Breast cancer, Biopsy, Breast magnetic resonance imaging
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